Course Description: Histophysiology (Biology 206) provides a comprehensive survey of the structure, composition, and function of tissues and their cellular and non-cellular components. Particular emphasis is placed on structural organization and structural – functional relationships in mammals, with occasional comparisons to other vertebrates. Recent histological research at Trinity may be considered, along with clinical aspects and controversies in tissue biology. In the laboratory, students learn fundamentals of tissue morphology through light microscopy and examination of electron micrographs. 1 1/4 course credits.
Prerequisites: Biology 182L and 183L (or their equivalents) are required. Students may also find some of the following Trinity courses to be useful for general background: Animal Physiology, Cell Biology, Neurobiology, Vertebrate Zoology, and Biochemistry. A background in general and organic chemistry also may be useful.
Required Text: Junqueira, L.C. and J. Carneiro (2010). Basic Histology: Text and Atlas. 12th ed. Lange Medical Books, McGraw Hill, NY.
Grading: Final letter grades are based on written exams, lab practicals, lab quizzes and hand-ins, and journal article summaries as indicated below. The lab plus the article summaries represent 40% of the points that can be earned in the course.
Course Schedule (Recent version)
Lecture 1. Introduction; Principles of Microscopy
LAB 1: INTRODUCTION TO MICROSCOPY; CHORDATE BODY PLAN
Lecture 2. Principles of Microscopy II
Lecture 3. Histological Techniques; Cell Organization
LAB 2: CELL STRUCTURE; HISTOLOGICAL TECHNIQUES
Lecture 4. Organelles and Cell Function
Lecture 5. Epithelial Cell Structure and Function
Quiz (Labs 1 & 2); LAB 3: EPITHELIUM & GLANDS
Lecture 6. Epithelium and Exocrine Glands
Lecture 7. Connective Tissue components; Adipose Tissue
LAB 4: Quiz (Lab 3); GENERALIZED CONNECTIVE TISSUES
Lecture 8. Lecture Exam 1
Lecture 9. Cartilage and Bone
LAB 5: Quiz (Lab 4); CARTILAGE & BONE
Lecture 10. Histogenesis of Cartilage and Bone; Muscle Tissue; Journal Article Summary #1 due
LAB PRACTICAL
Lecture 11. Muscle Organization and Contraction
Lecture 12. Neuron Structure and Function
LAB 6: MUSCLE & NERVOUS TISSUE
Lecture 13. Glial Elements; Nervous System Organization
Lecture 14. Blood and Hematopoiesis
LAB 7: Quiz (Lab 6); BLOOD & CARDIOVASCULAR SYSTEM
Lecture 15. Cardiovascular System
Lecture 16. Functional Organization of the Digestive Tract
LAB 8: Quiz (Lab 7); DIGESTIVE TRACT
Lecture 17. Digestive Tract II; Liver and Pancreas
Lecture 18. Mammalian Integument
LAB 9: Quiz (Lab 8): INTEGUMENT; RESPIRATORY SYSTEM
Lecture Exam #2
Lecture 19. Urinary System; Journal Article Summary #2 due
LAB 10: Quiz (Lab 9): KIDNEY; ENDOCRINE ORGANS
Lecture 20. Endocrine Organs
Lecture 21. Male Reproductive System
LAB 11: Quiz (Lab 10): REPRODUCTIVE SYSTEM
Practical application: ingestion/ digestion of Meleagris gallopavo
Lecture 22. Female Reproductive System
LAB 12: Review
Lecture 23. Female Reproduction II
Lecture 24. Implantation and Placentation in Mammals; Journal Article Summary #3
LAB 13: Final Lab Practical
Lecture 25. Research Lecture: Reptile Placentas
Final Exam