Course Description (Biology 350):  Electron microscopes are valuable research tools that have provided a wealth of information about cell structure and function. Using the transmission electron microscopy (TEM) laboratory in the Life Sciences Center, this course provides an introduction to cellular ultrastructure and to techniques through which it can be studied. Students will learn techniques of tissue fixation, embedding, sectioning (ultramicrotomy), and staining, as well as use of the TEM to visualize and photograph specimens. Microscopic structure of cells and tissues also will be studied using prepared specimens. This course is primarily designed for students interested in doing research in biology, biochemistry, or neuroscience.

Prerequisites: Biology 182L and 183L, and permission of the instructors.